Fear and politics took away our effective medicines

Imagine a world where substances that could actually help people with depression, PTSD, addiction, and even, as it turns out, to treat psychopathy and be effective in the matter of moral enhancement, lay forgotten on history’s dusty shelves, chained by bureaucratic red tape. The discussion centers around psychedelics – LSD, psilocybin, and other enigmatic, vibrant substances that are now back in vogue thanks to the renewed interest of many scientists and therapists.

Back in mid-20th century, psychedelics were a genuine star in science. Scientists saw considerable potential within them, and psychotherapists were enthusiastic about the possibility of assisting individuals in experiencing profound, transformative experiences. Naturally, skepticism existed, but it was justified by a lack of robust methods and clear protocols to confidently assess the impact of psychedelics on people. Essentially, this represented typical scientific skepticism—essential for any novel research direction. However, as usual, political forces intervened.

When counterculture figures in the United States, protesting the Vietnam War, began utilizing psychedelics for recreational purposes and to “expand consciousness,” politicians became concerned. Authorities disapproved of this “uncomfortable freedom,” as psychedelics symbolized cultural rebellion and dissent, undermining government authority and control, and they quickly designated them a scapegoat. “Drugs! Dangerous! Ban Them!” – this is what newspaper headlines declared.

Naturally, scientists also found themselves in trouble. Research on psychedelics was halted because authorities effectively choked off any efforts to study these substances. Moreover, government restrictions extended beyond well-known psychedelic compounds to encompass all substances affecting 5-HT2A receptors in the brain – crucial elements of the mechanism behind classic psychedelics. The American government implemented strict legal limitations; any experiments with psychedelics demanded extensive bureaucratic approvals and stringent control by governmental bodies. This meant that only a select few laboratories could access such research.

And now, decades later, scientists are cautiously opening this door again. It turns out that in the right doses and under the control of professionals, psychedelics are quite safe, and the problem most often arises from uncontrolled use of excessively large doses, when these substances truly turn into “malevolent drugs stealing reason,” rather than powerful therapeutic tools. Research is also being conducted on finding the most effective dosages, with maximum therapeutic effect and minimal side effects. In general, modern research suggests that within controlled sessions, psychedelics are not only safe and do not disrupt human cognitive and affective abilities, but also enhance empathy, help cope with trauma, and even significantly reduce aggression levels.

Furthermore, now work is underway to create new molecules that will retain all the advantages of original psychedelic substances, but minimize potential risks. Compounds are being developed that selectively affect specific brain receptors, allowing for therapeutic effects without unwanted side effects such as hallucinations or excessive stimulation. It’s quite something – science has come very far, and now we can be witnesses to a second psychedelic renaissance.

The irony is that all these years skepticism towards psychedelics was not so much scientific as it was political. So maybe it’s enough already to stop fearing the ghosts of the past? Because science clearly shows us that in the case of psychedelics, we should trust research rather than scary stories from the last century. Today, psychedelics can be successfully used for therapeutic purposes, including even such an important direction as enhancing the function of the mechanism of violence inhibition, bio-amplifying morality and treating psychopathy.

Voluntarist, Bitarchy

The aggressor will not complain to anyone if his violence inhibitor is strengthened

According to numerous studies, psilocybin is capable of strengthening the violence inhibitor for a very long, or even permanent period, and also weakening the tendency toward authoritarian views, with just a couple of doses equivalent to 5-10 grams of dried mushrooms. It should be noted immediately that this substance is classified by the authorities of the RF and many other countries as a prohibited psychotropic agent. But such a ban could lead to one interesting scenario, where an aggressive degenerate, in the event that their violence inhibitor is strengthened, will simply have nowhere to complain!

Imagine a situation where some degenerate rapist had those same “mushrooms” slipped into their food; they found out about it and decided to snitch. They went to the police station… but instead of taking a report and searching for some anti-violence fighters, they filed an administrative charge against the degenerate himself for drug use, with all the ensuing consequences—registration with a narcologist, suspension of driver’s licenses of all categories, a ban on holding certain positions (doctor, lawyer, official), and ultimately, even dismissal from work.

The degenerate will think about this for a bit and decide: “Better to keep my mouth shut, not even tell my friends, otherwise if they find out, I’ll never see a normal life again! And besides, no one will care; I’ve said it myself many times that ‘the sheriff isn’t interested in Indian problems’ and pushed for ‘strict liability,’ without ever imagining that it could affect me as well.”

Such a scenario is entirely expected, because how is a rapist even going to prove they are right?! And in many jurisdictions, it’s unlikely that anyone would care—they would more likely just try to use him to fill a quota, especially if he has already managed to get flagged for committing violence in the past.

Voluntarist, Bitarch

Psychopathy as a predictor of authoritarian political views and what can be done about it

Many studies have examined the psychological foundations of human political views, as various personality traits influence ideological attitudes, opinions, and values. Of particular interest is whether there is a link between psychopathic predispositions and a tendency toward authoritarian political positions, which has also been studied. Furthermore, there are studies indicating one interesting way in which a person’s authoritarian tendencies can be reduced.

A rather illustrative study by Zlatko Šmra concerns the question of whether psychopathy, as well as indicators of positive and negative affect, predicts a person’s inclination toward totalitarian political ideology. In this study, psychopathy was divided into 4 factors: interpersonal (tendency to deceive and manipulate people), affective (lack of empathy, guilt, and remorse), lifestyle (impulsivity, parasitism, and irresponsibility), and antisocial (poor behavioral control and an excessive tendency to commit criminal offenses). For simplicity, we will define the first two factors as primary psychopathy and the others as secondary. In turn, positive and negative affect reflect how much a person is inclined to exhibit enthusiasm and activity, or rather, some unpleasant states of mood, such as anger and nervousness. Finally, totalitarian political ideology implies a person’s high need for state social regulation, their acceptance of life under a dictatorship, the denial of individual freedom, as well as support for repressive methods and procedures. It should be noted that in this case, we are referring to both radical left and radical right ideologies.

In a sample of 386 students aged 18 to 29, it was shown that traits of primary psychopathy significantly predict an individual’s predisposition toward totalitarian political ideology, whereas the link with secondary psychopathy is virtually zero. However, psychopathy scores in general, and secondary psychopathy in particular, predict the presence of negative affect, which in turn also increases a person’s predisposition toward totalitarian political ideology to a certain extent. These results provide a valuable contribution to the understanding of how individuals adopt totalitarian views.

But understanding the problem is not where it ends. In one study, it was shown that the administration of psilocybin sustainably reduces people’s predisposition toward authoritarian views on the libertarian-authoritarian scale (the effect was observed even a year after administration). This substance, which belongs to the psychedelics, exerts a strong prosocial and empathic effect on humans, due to which it is proposed for the therapy of psychopathy as well.

The primary effect of psychedelics on the human brain is the activation of serotonin 2A receptors. However, studies show, that the prosocial effect in the case of their use is likely due to serotonin 1A receptors. This means that selective anti-aggressive agents that act specifically on this type of receptor and produce minimal or no side effects or influence on other behaviors could potentially be effective in the therapy of psychopathy (strengthening the violence inhibitor) and reducing human authoritarianism. As a result, we gain the possibility of effective and safe treatment of psychopathy, as well as its consequences, such as authoritarian tendencies.

Voluntarist, Bitarch